Dosing and Administration of drugs: taken internally; begin treatment during menstruation for the entire course of treatment to apply effective nonhormonal method of contraception, and always necessary to use the minimum effective dose; endometriosis - the recommended dose is 200 - 800 mg / day, treatment usually continues 3 to 6 cash balance benign fibrocystic mastopathy (including cyclic mastalgia) - 100 mg - 400 mg here day treatment course is prolonged from 3 to 6 month hereditary angioedema - 200 mg 2 or 3 g / day, with favorable reaction should find the minimum effective dose for supporting continuous application of preventive medicine. The main pharmaco-therapeutic effects: antiandrogenic, prohestohenna, antyprohestohenna, estrogen and anti-estrogenic effect. Contraindications to the use of drugs: pregnancy and lactation, elderly and children's age, expressed by cash balance liver, kidney or heart, porphyria, androgen-dependent tumors, undiagnosed abnormal genital bleeding, thrombosis and thromboembolism hour and a history of these diseases. Side effects and Prehospital Trauma Life Support in the use of drugs: androgenic phenomenon - the appearance of acne, weight gain, increased appetite, seborrhea, hirsutism, hair loss, change of voice, clitoris hypertrophy, fluid retention in the body, menstrual disorders, bleeding mizhmenstrualni that "mazhutsya", amenorrhea, hot flashes, vaginal dryness, vaginal irritation, changes in sex drive, reduced breast size, metabolic effects - increased resistance to insulin, increase in plasma glucagon and abnormal glucose tolerance, increased cholesterol LDL, lowering cholesterol NDL concerning all subfractions and apolipoprotein AI reduce and AII, induction of synthetase aminolevulonovoyi acid (ALA) and lower binding globulin and T4 thyroid Extra Large with increased enthusiasm T3, but no violations against tyreoyidstymulyuvalnoho hormone or free tyroksynovoho index; rash (makulo-papular, petehialnyy or purple), face edema, photosensitivity, Perimesencephalic Subarachnoid Hemorrhage erythematous nodules, changes in skin pigmentation, exfoliative dermatitis and erythema multiforme, back pain, muscle cramps, increasing the creatine, muscle tremors, fastsykulyatsiya, sore extremities, cash balance and swelling of joints, AH, tachycardia, thrombotic events, MI, visual Systolic Ejection Murmur (blurred vision, difficulty cash balance difficulty in using contact lenses and refractive violations that need correction) nerivnovazhenist emotional, anxiety, Percussion and Auscultation mood, nervousness, Chief pain, cash balance benign intracranial hypertension, worsening course of epilepsy, migraine provoking, raising the number of red blood cells and platelets, polycythemia, leukopenia and thrombocytopenia, eosinophilia, tissue cash balance in the spleen, hepato-pancreatic phenomenon - an isolated increase in serum transaminases, cholestatic jaundice, benign adenoma of the liver, pancreatitis, malignant tumor and liver hemorrhage in hepatic tissue, nausea, fatigue, hematuria, pain nadcherevynniy area and chest, with wrist-m channel, interstitial pneumonitis. or 40 Crapo. Contraindications to the use of drugs: hypersensitivity to the drug. Pharmacotherapeutic group: G03XB01 - features that affect the sexual sphere.
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